Falk Forum
OPTIMISING MANAGEMENT STRATEGIES IN GUT INFLAMMATORY DISEASES

Dr. Falk Pharma Australia hosted a one-day meeting in Sydney on June 22, 2024. This highly attended event featured leading experts from across Australia who discussed and debated the latest strategies in IBD management and overall patient care. Whether you missed the meeting or attended and wish to review the content, you can access it here at your convenience. Please note that the opinions expressed by the speakers are not necessarily those of Dr. Falk Pharma Australia, and some therapeutic interventions discussed are not currently TGA-approved.

WATCH THE SESSIONS

OPTIMISING PHARMACOLOGICAL STRATEGIES IN IBD

The old drugs – still on the menu:
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Mesalazine

Associate Professor Gregory Moore
Monash Medical Centre, VIC
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Introduction
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Mesalazine
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The history of mesalazine
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The discovery of sulphasalazine
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SASP among the first RCTs
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The Pharmacokinetics of sulphasalazine
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Proof that 5-ASA is the active ingredient
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5-ASA Pro-drugs with AZO bonds
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pH-dependent formulations
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Eudragit gastro-resistant polymers
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Salofalk Granules
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Mezavant Tablets
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Pentasa
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Patient factors that might affect 5-ASA delivery
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5-ASA formulation drug dissolution profiles
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5-ASA release from Mezavant vs ASACOL
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Mesalazine clinical guidelines
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ECCO guidelines – induction therapy
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5-ASA meta analysis and Cochrane review
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ECCO guidelines – maintenance
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Tips and tricks
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Summary
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Immunomodulators – genuine therapy or a route to biologics?

Dr Aviv Pudipeddi
Concord Repatriation General Hospital, NSW
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Introduction
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Thiopurines in IBD
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Methotrexate in Crohn’s Disease
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Summary
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New recipes to make infliximab tastier?

Dr John Chetwood
St Vincent’s Hospital, VIC
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Introduction
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Top-down therapy
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Subcutaneous infliximab
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TNF use in elderly
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Proactive TDM
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Proactive obesity treatments
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The future
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Choosing advanced therapy from the smorgasboard

Dr Lena Thin
Fiona Stanly Hospital, WA
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Introduction
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Disease location and severity
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Comparative efficacy – potency of treatment
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Impact of obesity
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Comparative safety
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Does sequence matter?
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Summary
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Panel Discussion

OPTIMISING THE IGNORED ISSUES IN IBD – WHAT SHOULD I BE DOING?

Rotating Sessions:

1 - Disordered eating behaviours - How to recognise and manage

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Peter Gibson
Monash University, VIC
Alice Day
The Queen Elizabeth Hospital, SA
Simon Knowles
Swinburne University of Technology, VIC
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Peter Gibson
Monash University, VIC
Alice Day
The Queen Elizabeth Hospital, SA
Simon Knowles
Swinburne University of Technology, VIC
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Peter Gibson
Monash University, VIC
Alice Day
The Queen Elizabeth Hospital, SA
Simon Knowles
Swinburne University of Technology, VIC

2 - Body composition - How to measure it in clinical practice, but does it matter?

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Rob Bryant
The Queen Elizabeth Hospital and University of Adelaide, SA
Anke Nguyen
Monash Medical Centre, VIC
Jess Fitzpatrick
Mind + Gut Clinic, VIC
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Rob Bryant
The Queen Elizabeth Hospital and University of Adelaide, SA
Anke Nguyen
Monash Medical Centre, VIC
Jess Fitzpatrick
Mind + Gut Clinic, VIC
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Rob Bryant
The Queen Elizabeth Hospital and University of Adelaide, SA
Anke Nguyen
Monash Medical Centre, VIC
Jess Fitzpatrick
Mind + Gut Clinic, VIC

3 - DGBI in IBD - Does it exist, how to assess and how to manage?

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Mayur Garg
University of Melbourne, VIC
Rebecca Burgell
Alfred Health, VIC
Taryn Lores
Royal Adelaide Hospital, SA
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Mayur Garg
University of Melbourne, VIC
Rebecca Burgell
Alfred Health, VIC
Taryn Lores
Royal Adelaide Hospital, SA
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Mayur Garg
University of Melbourne, VIC
Rebecca Burgell
Alfred Health, VIC
Taryn Lores
Royal Adelaide Hospital, SA

UPSKILLING FOR NEW DIMENSIONS IN GASTROENTEROLOGICAL PRACTICE

Eosinophils along the GIT:
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Treat-to target strategies in eosinophilic oesophagitis – Short- and long-term considerations

Associate Professor Santosh Sanagapalli
St Vincent's Hospital, NSW
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Introduction
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What is this target in EOE?
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Initial therapeutic approach
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Inflammation vs fibrosis
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Steroids, PPIs, elimination diets and dilations
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Positioning of therapies
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Combination therapy in EOE
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Long-term management
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Summary
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How to interpret their presence distal to the oesophagus

Dr Jesica Makanyanga
Fiona Stanley Hospital, WA
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Introduction
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Patient case study
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Eosinophilic GI Diseases
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When to suspect an eosinophilic GI disease
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Initial evaluation
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Diagnostic criteria
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Imaging
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Diseases which cause eosinophils in GI tract
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Therapy
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Diet
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Corticosteroids
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Corticosteroid dependance
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Biologics
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Summary
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Panel Discussion

Microbiota along the GIT:
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Should I test and how do I interpret the results?

Associate Professor Craig Haifer
St Vincents Hospital, NSW
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Microbial manipulation in IBD – Feeding the bugs

Dr Heidi Staudacher
Deakin University, VIC
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Microbial manipulation in IBD – Killing, adding or renovating?

Dr Sasha Fehily
St Vincent’s Hospital, VIC
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Panel discussion

SPEAKER, CHAIR AND STEERING COMMITTEE BIOGRAPHIES

person1
Professor Peter Gibson
Monash University, VIC
person2
Doctor Yoon-Kyo An
Mater Hospital Brisbane, QLD
person3
Associate Professor Mayur Garg
University of Melbourne, VIC
person4
Doctor Abhey Singh
Fiona Stanley Hospital, WA
person5
Associate Professor Robert Bryant
University of Adelaide, SA
person6
Doctor Sudarshan Paramsothy
University of Sydney, NSW
person1
Professor Peter Gibson
Monash University, VIC
person2
Doctor Yoon-Kyo An
Mater Hospital Brisbane, QLD
person3
Associate Professor Mayur Garg
University of Melbourne, VIC
person4
Doctor Abhey Singh
Fiona Stanley Hospital, WA
person5
Associate Professor Robert Bryant
University of Adelaide, SA
person6
Doctor Sudarshan Paramsothy
University of Sydney, NSW
Taryn Lores
Taryn Lores
Royal Adelaide Hospital, SA
Lena thin
Dr Lena Thin
Fiona Stanly Hospital, WA
Anke Nguyen
Dr Anke Nguyen
Monash Medical Centre, VIC
Alice Day
Dr Alice Day
The Queen Elizabeth Hospital, SA
John Chetwood
Dr John Chetwood
St Vincent’s Hospital, VIC
Craig
Associate Professor Craig Haifer
St Vincents Hospital, NSW
Heidi Staudacher
Dr Heidi Staudacher
Deakin University, VIC
Santosh Sanagapalli
Associate Professor Santosh Sanagapalli
St Vincent’s Hospital, NSW
Jessica Fitzpatrick
Jessica Fitzpatrick
Mind + Gut Clinic, VIC
Aviv Pudipeddi
Dr Aviv Pudipeddi
Concord Repatriation General Hospital, NSW
Simon Knowles
Associate Professor Simon Knowles
Swinburne University of Technology, VIC
Rebecca Burgell
Associate Professor Rebecca Burgell
Alfred Health, VIC
Professor-Susan-Connor-2
Professor Susan Connor
Liverpool Hospital, NSW
Jesica Makanyanga
Dr Jesica Makanyanga
Fiona Stanley Hospital, WA
Sasha Fehily
Dr Sasha Fehily
St Vincent’s Hospital, VIC
Greg Moore
Associate Professor Greg Moore
Monash Medical Centre, VIC
Ruth Hodgson
Dr Ruth Hodgson
The Prince Charles Hospital, QLD

This content is intended for Healthcare Professionals only.
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Website: www.drfalkpharma.com.au Tel: 1800 DRFALK (1800 373 255). Email: admin@drfalkpharma.com.au
Date of preparation July 2023. IBD-2024-1334. DRFAL24046.